Cell Segmentation via Shape Modeling

نویسندگان

  • Kelvin Gu
  • Michael Mayhew
  • Alexander Hartemink
چکیده

Abstract. We develop a novel generative model for arbitrary 2D shapes, based on multiscale deformation. We demonstrate how our model can be used to segment objects within an image by fitting a shape-sensitive contour to each object’s boundary. We demonstrate our model by performing segmentation on di↵erential interference contrast microscopy (DIC) images of yeast, where many cells possess aberrant shape and boundaries that contain major gaps or touch other cells. Our method can be seen as a ‘shape-sensitive’ and statistical active contour.

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تاریخ انتشار 2011